How have race and racism affected the lived experiences of individuals and societies across the globe? The field of genetics has been a cornerstone in discourses on the origins, meanings, and consequences of the concept of race and racial classifications in humans. This transdisciplinary, international comparative course examines the contributions of genetics (and genomics) and other biological sciences as well as social sciences to both the manufacturing and dispelling of notions of race and racial hierarchies. We will explore ethical, psychosocial, cultural, societal, scientific, and clinical issues concerning historical and contemporary intersections among race, human variation, human identity, and human health. Through large and small group interactions, students will co-create practical strategies for dismantling racial ideologies and advancing narratives that foster equity and sustained global transformation.